Biotin and derivatives
Medchemexpress LLC 5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid, 1-(1,1-dimethylethyl) 20-(2,5-dioxo-1-pyrrolidinyl) ester | 2055040-78-1 | 96.9% | 506.54 | 1 G
Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound facilitates the targeted degradation of proteins by exploiting the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Azido-PEG3-O-NHS ester | 2110448-98-9 | 95% | C13H20N4O8 | 100 MG
Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent features an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN group-containing molecules.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
eMolecules 2280998-74-3 | Medchem Express | m-PEG11-acid | 50mg | 721309591 | HY-140501 | MFCD27977512 | 544.635 | C24H48O13
Ambeed | 2-(4-Carbamimidoylphenyl)acetic acid hydrochloride | 100mg | 490510431 | A142490 | 52798-09-1 | MFCD11505975 | 214.650 | C9H11ClN2O2
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Medchemexpress LLC Biotin-PEG2-NHS ester | 596820-83-6 | 96.7% | C21H32N4O8S | 25 MG
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. One ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand is for an E3 ubiquitin ligase
- Other ligand is for the target protein
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Mal-PEG6-NHS ester | 1599472-25-9 | MFCD20926374 | 98.0% | 530.52 g/mol | C23H34N2O12 | 1 G
Mal-PEG6-NHS ester is a non-cleavable ADC linker containing a maleimide reactive group, a six-unit polyethylene glycol (PEG6) spacer, and an N-hydroxysuccinimide (NHS) ester for amine coupling. It is supplied for research use in synthesis and bioconjugation workflows.
- Purity 98.0%.
- Cas number 1599472-25-9.
- Molecular weight 530.52 g/mol.
- Chemical formula C23H34N2O12.
- Soluble in DMSO at 100 mg/mL (in vitro; ultrasonic recommended).
- Suggested in vivo formulations provided for dosing preparations.
- For research use only; not for use in patients.
- Pack quantity 1 G.
Medchemexpress LLC N-succinimidyl 4-(dimethylamino)benzoate | 58068-85-2 | MFCD16875522 | 99.0% | 262.26 g/mol | C13H14N2O4 | 10 MG
DMABA NHS ester is an N-hydroxysuccinimide (NHS) ester reagent used to derivatize primary amine groups of phosphatidylethanolamine (PE) lipids, enabling selective detection by mass spectrometry. It is supplied as a white to off-white solid with high purity and recommended cold storage to preserve activity.
- Enables selective labeling of PE lipids for precursor ion scanning.
- Improves detection sensitivity in electrospray tandem mass spectrometry.
- High purity supports reliable analytical results.
- Stable as supplied with recommended low-temperature, moisture-free storage.
- Compatible with isotope-labeled DMABA analogs for comparative analyses.
Medchemexpress LLC AF647-NHS ester (triTEA) | 407627-61-6 | 99.7% | 10 MG
AF647-NHS ester (triTEA) is a far-red fluorescent NHS ester reagent used to label primary amines for fluorescence detection. Supplied as a purple solid, it is optimized for conventional and instantaneous detection and is soluble in DMSO when warmed or sonicated.
- Far-red fluorescent NHS ester for amine conjugation.
- Excitation: 635 nm (conventional) / 620 nm (instantaneous).
- Physical form: purple to dark purple solid.
- Purity: 99.74% as reported by manufacturer.
- Solubility: DMSO 20 mg/mL; use freshly opened DMSO and apply ultrasonic/heat to 60°C as needed.
- Storage: protect from light and store under nitrogen; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for patient use.
Medchemexpress LLC Mal-PEG8-NHS ester | 2055033-05-9 | 99.0% | 50 MG
Mal-PEG8-NHS ester is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It appears as a colorless to light yellow viscous liquid, intended solely for research applications.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
- Appearance: viscous liquid
- Color: colorless to light yellow
- Molecular formula: C27H42N2O14
- Molecular weight: 618.63
- Solubility in DMSO: ≥ 100 mg/mL
Medchemexpress LLC Acid-C2-PEG4-C2-NHS ester | 1343476-41-4 | 98.0% | 100 MG
Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker. This chemical reagent is used in the synthesis of PROTACs and is intended for research use only. It appears as a colorless to light yellow liquid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
- Consists of two different ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase, the other to the target protein
Medchemexpress LLC Fmoc-PEG1-CH2CH2-NHS ester | 1807521-05-6 | 96.3% | 250 MG
Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteeasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- PROTACs exploit the intracellular ubiquitin-proteasome system
- PROTACs selectively degrade target proteins
Medchemexpress LLC m-PEG14-NHS ester | 00-00-0 | 95.0% | C34H63NO18 | 10MG
m-PEG14-NHS ester is a methoxy-terminated polyethylene glycol (PEG) reagent bearing an N-hydroxysuccinimide (NHS) active ester. Supplied as a solid for laboratory use, it is intended for use as a PROTAC linker or for PEGylation to attach PEG chains to amine-containing molecules via stable amide bonds.
- Methoxy-terminated PEG with an NHS active ester.
- Reacts with primary amines to form stable amide bonds.
- Molecular weight ~773.86 Da.
- Chemical formula C34H63NO18.
- Purity ≥95.0%.
- White to off-white solid appearance.
- Store sealed, away from moisture and light; in solvent: -80°C for 6 months, -20°C for 1 month.
- Available in small research pack sizes.
Medchemexpress LLC Biotin-PEG11-amine | 1418022-42-0 | MFCD21363309 | 99.9% | C34H66N4O13S | 10MG
Biotin-PEG11-amine is a biotin-labeled polyethylene glycol linker with a terminal primary amine, supplied as a solid for research use. It is intended for biotinylation and incorporation into PROTACs or other conjugates, offering improved aqueous solubility and a flexible spacer to reduce steric hindrance during coupling reactions.
- Provides a terminal primary amine for coupling to carboxyl or phosphate groups.
- Contains an 11-unit PEG spacer to improve solubility and flexibility.
- Supports biotin-based affinity capture and detection workflows.
- Supplied as a white to off-white solid with high purity.
- Recommended storage: -20°C protected from light; in solvent, -80°C for long-term storage.
Medchemexpress LLC L-biotin (unnatural enantiomer of biotin) | 21788-37-4 | MFCD22373639 | 99.5% | 244.31 g·mol⁻¹ | C10H16N2O3S | 1 ML
L-biotin is the unnatural enantiomer of biotin supplied as a research reagent. It binds streptavidin in vitro and is provided as a ready-to-use 10 mM solution in DMSO (1 mL) or as solid powder in multiple pack sizes. Recommended storage conditions are -20°C for powder, and -80°C for stock solutions (up to 6 months).
- Unnatural enantiomer of biotin
- Binds streptavidin in vitro
- Available as 10 mM DMSO solution or solid powder
- High purity (>99%)
- Soluble in DMSO at high concentration
- Powder storage: -20°C; stock solution storage: -80°C (6 months)
Medchemexpress LLC m-PEG14-NHS ester | 95.0% | 773.86 | 25 MG
m-PEG14-NHS ester is a PEG-based PROTAC linker. This chemical is intended for laboratory use in the synthesis of PROTACs.
- Supplied as a white to off-white solid
- Stable under recommended storage conditions
- Recommended storage at -20°C, sealed storage, away from moisture and light
- Shipping at room temperature if less than 2 weeks
- Has a purity of 95.0%
- Molecular weight is 773.86
![eMolecules 58-85-5 | D-Biotin | Oakwood Chemicals | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 480169794](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000160341.jpg-250.jpg)
eMolecules 58-85-5 | D-Biotin | Oakwood Chemicals | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 480169794
D-Biotin | Oakwood Chemicals | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 480169794